Custom synthesis
You know the molecule. We make it, whether it’s been made before or not.
- Out-of-stock and discontinued compounds
- New compounds that have never been made
- Milligrams for screening to kilogram batches
Custom synthesis and contract research, milligrams to kilograms.
OmniChem USA makes the compounds you can’t find in a catalog: modified nucleosides, phosphoramidites, protected amino acids, and other fine chemicals. We’ve made research chemicals since 1990.
- No minimum order
- HPLC, NMR and MS on every CoA
- US and international shipping
Two ways to work with us
Bring us a molecule you need made, or a chemistry problem you need solved.
Contract research
You have a synthesis problem that needs experienced hands at the bench.
- Route design for new targets
- Route improvement before scale-up
- Analogs, intermediates, and building blocks
Chemistry we know well
For more than three decades we made DNA, RNA, and peptide synthesis reagents for research labs. That work is where our deepest experience comes from.
Nucleosides and oligonucleotide chemistry
- DNA and RNA phosphoramidites, standard and modified
- Protected and modified nucleosides and nucleotides
- CPG solid supports for DNA, RNA, and modified sequences
- 5′ and 3′ labeling dyes and modifiers
- Biotin and other conjugation reagents
Amino acids and peptide chemistry
- Protected amino acid derivatives
- Amino acid building blocks made to your specification
- Peptide synthesis and coupling reagents
Working on something else? Send us the structure anyway. If it isn’t a fit, we’ll say so.
Research chemicals since 1990
OmniChem USA started in 1990 supplying high-purity biochemicals to molecular biology and life science labs: DNA and RNA synthesis reagents, nucleotides, amino acid derivatives, and peptide synthesis reagents.
- Founded
- 1990
- Services
- Custom synthesis, contract research
- Specialties
- Nucleosides, oligonucleotide reagents, amino acids, peptides
- Scale
- Milligrams to kilograms
Common questions
Anything else, email us or call (800) 644-1742.
What can OmniChem USA make?
Small-molecule research compounds, with our deepest experience in nucleoside, nucleotide, phosphoramidite, amino acid, and peptide chemistry. That covers known compounds that are out of stock or discontinued as well as new compounds that have never been made. Send the structure and we’ll tell you whether it’s a fit.
What quantities do you handle?
From milligrams for screening up to kilograms for scale-up. There’s no minimum order.
What analytical data comes with a custom compound?
Every compound ships with a certificate of analysis that includes HPLC, NMR, and mass spectrometry data. If you need a specific method or additional tests, put it in your request.
What should a quote request include?
The structure (a ChemDraw or MOL file, a SMILES string, or a CAS number), the quantity, your target purity, the analytical data you need, and your timeline. If you know a literature route, include the reference.
Is my project kept confidential?
Yes. We’re glad to sign your confidentiality agreement before you share structures or project details.
Do you ship outside the United States?
Yes, we ship within the US and internationally. Callers outside the US can reach us at +1 (847) 687-7842.